MULTI-ACT – Bringing research closer to patients and society

The MULTI-ACT project aims at bringing research on brain diseases closer to patients and society. Higher life expectancy among Europeans has caused an increase in the number of patients with brain diseases, such as Alzheimer’s, Parkinson’s, Multiple Sclerosis and many other disorders. Brain ill-health currently affects 179 million individuals in Europe and will affect one in three Europeans during their lifetime. The five most prevalent brain diseases in Europe are anxiety disorders, migraine, mood disorders, addiction and dementia. It is therefore of utmost importance to develop a research model that produces results that have a real impact on the lives of these patients and their caregivers.

Despite the significant progress in terms of the mechanistic underpinnings of neurological diseases at the molecular, cellular and circuit levels, the translation of these discoveries into therapies remains a critical challenge. Effective and efficient collaboration and cooperation among the various initiatives is often identified as a key success factor to achieve maximum impact of brain research. Therefore, it is mandatory to foster innovation by building effective collaboration along the entire drug-discovery and development pathway, with the involvement of all stakeholders. However, most multi-stakeholder initiatives have lacked shared measurements of impact and supporting infrastructures to enable true alignment of efforts and accountability of results.

The MULTI-ACT project will last 3 years with a budget of €3.5 million. It brings together leading European society and patient organizations, research and higher education institutions, governmental organizations and technological organizations. MULTI-ACT will be coordinated by the Italian Multiple Sclerosis Society Foundation (FISM), as member of the International MS Federation (MSIF), a “boundary organization” between science and patients.

Objectives and methodology

The MULTI-ACT project aims to increase the impact of health research on people with brain diseases. It will create and implement a new model allowing for the effective cooperation of all relevant stakeholders and be applicable in defining the scope of health research and innovation as well as new metrics for the evaluation of its results.

The MULTI-ACT project will work with patients and patient organizations, academics, private and public stakeholders to develop brand new tools to assess the value of research.

For more information on the project, visit You can also follow MULTI-ACT on Twitter @MULTIACTProj.


This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under the Grant Agreement No. 787570.
This page and the publications contained herein only reflects the author’s views. The European Union is not liable for any use that might be made of the information contained in this page and publications.