PREPACT – A receptivity assessment for hMPV and RSV diagnosis in older adults

Project Status: ONGOING (September 2024 – December 2025)

What aims and scope

PREPACT aims to address receptivity and identify drivers and barriers towards providing timely and effective diagnosis of RSV and hMPV in older adults (defined as people aged 60-65+, including at-risk populations), with special emphasis on testing and surveillance. PREPACT will also develop recommendations to enhance receptivity levels in selected European countries, with specific attention to hMPV, which is still significantly under-diagnosed and under-recognised.

How it became possible

EHMA will lead in setting up an expert focus group that will advise on the project methodology, including the methodology of the literature review on the diagnosis and impact of RSV and hMPV. Focusing on France, Germany, Italy, Spain, and the UK, data regarding receptivity will be collected following expert input from the aforementioned focus group. The data collection will include the administration of a survey and/or one-on-one interviews with experts in outpatient and hospital settings from the selected countries.

Where EHMA delivers

The baseline receptivity report will be developed in two phases. First, a framework will be set based on inputs from the focus group and the literature review. The framework will be shared with the sponsor for initial feedback. Upon completion of the data collection, the first draft of the report will be developed and submitted to the focus group and the sponsor for feedback. The feedback will be integrated into the final version of the report. A session at the European Health Management Conference 2025 (in Rennes, France, 4-6 June 2025) will be used to present the preliminary results and to facilitate a broader discussion on the topic of prevention and immunisation in older adults. Finally, the baseline receptivity report will be disseminated via EHMA and Sanofi channels.

EHMA has expertise in immunisation research, including the health system burden and disruption caused by RSV in Europe. The EHMA RSV survey (Aug-Dec 2021) on the health system burden and disruption took a comprehensive ‘whole systems approach’ to document and characterise the public health impact of RSV across the care spectrum. EHMA conducted a comprehensive stakeholder mapping exercise to identify, contact, and successfully engage the European paediatric community, primary care, and allied healthcare professionals. A total of 45 European and national-level medical organisations were contacted and successfully mobilised for survey dissemination. In 2024, EHMA has also been conducting a study on the burden of pneumococcal diseases in older adults in selected European countries, namely Austria, Belgium, France, Italy, and Portugal.

Why will you benefit

At EHMA, our mission is to ensure that Europe’s citizens and communities benefit from health systems that are built on effective, evidence-based practices. Through this work on receptivity levels for diagnosing RSV and hMPV in older adults, we aim to empower managers, educators, providers, researchers, and policymakers with the knowledge and tools needed to improve health management. PREPACT fosters collaboration and innovation, supporting research and development within the EHMA network. The insights gathered will be shared widely and transformed into practical solutions through joint initiatives, ensuring they reach healthcare professionals and decision-makers across Europe.

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Prof. Sandra C. Buttigieg, University of Malta, Malta

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